Atovaquone

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Atovaquone is a naphthalene compound with proven efficacy against Pneumocystis spp fungi and certain protozoa such as Toxoplasma and haemoplasmas.

This drug appears effective against Toxoplasma-induce choroidoretinitis[1].

Recommended doses in cats is 13.3 mg/kg with fatty meal orally every 8 hours for 21 days[2]. It appears superior to imidocarb against haemoplasma parasites.

Agaisnt haemoplasmas, it is best used in combination - atovaquone (15 mg/kg p.o. q8h) and azithromycin (10 mg/kg p.o. q24h)[3].

References

  1. Winterhalter S et al (2010) Does atovaquone prolong the disease-free interval of toxoplasmic retinochoroiditis? Graefes Arch Clin Exp Ophthalmol 248(8):1187-1192
  2. Rand, J (2006) Problem-based feline medicine. Saunders Elsevier, Sydney
  3. Cohn LA et al (2011) Efficacy of atovaquone and azithromycin or imidocarb dipropionate in cats with acute cytauxzoonosis. J Vet Intern Med 25(1):55-60