Feline morbillivirus

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Morbillivirus

The Morbillivirus is a paramyxovirus viral disease which has been reported in cats recently[1] from samples taken from urine, rectum and blood in cats from Hong Kong and Japan[2].

Diagnosis of virus is based on PCR testing allied with clinical signs.

Clinical signs are usually associated with tubular interstitial nephritis, with vomiting and diarrhoea commonly seen initially.

Pathological changes noted during histopathological examination of affected cats revealed interstitial inflammatory infiltrate and tubular degeneration/necrosis in kidneys, with decreased cauxin expression in degenerated tubular epithelial cells.

Supportive treatment (IV fluids) is recommended at this stage.


References

  1. Woo, PC et al (2012) Feline morbillivirus, a previously undescribed paramyxovirus associated with tubulointerstitial nephritis in domestic cats. http://www.pnas.org/content/suppl/2012/03/13/1119972109.DCSupplemental
  2. Park ES et al (2014) Identification of a natural recombination in the F and H genes of feline morbillivirus. Virology 468-470C:524-531