From Ferret

Pleuropneumonia is a bacterial infection in ferrets caused by Pseudomonas luteola.

This disease is relatively uncommon, but affected ferrets present with varying degrees of acute illness.

Clinical signs arecharacterisized by lower respiratory tract disease, with fever, dyspnea and anorexia commonly reported[1]. There is a high mortality rate associated with this disease.

Diagnosis is usually based on presenting clinical signs supported with bacterial culture of thoracic fluids obtained by thoracocentesis or at postmortem.

Distemper would be an important differential diagnosis.

Histolopathological examination usually reveals a necrotizing-pyogranulomatous pleuropneumonia and lymphadenitis which is often fatal.

Treatment would rquire oxygen therapy and aggressive use of broad-spectrum antimicrobials.


  1. Martínez J et al (2012) Pyogranulomatous pleuropneumonia and mediastinitis in ferrets (Mustela putorius furo) associated with Pseudomonas luteola Infection. J Comp Pathol 146(1):4-10